EBV相关淋巴组织增生性疾病的分类进展

北京白癜风医院那家好 http://wapyyk.39.net/bj/zhuanke/89ac7.html

（2）急性传染性单核细胞增多症

定义和临床特征：

Thisinfectiousdisorderischaracterizedbysorethroat,fever,markedlyenlargedtonsils,andlymphadenopathy,particularlycervicallymphnodes.

这种感染性疾病的特点是咽喉痛、发烧、扁桃体明显肿大、淋巴结肿大，特别是颈部淋巴结。

Mostinitialinfectionsoccurasymptomaticallyinchildrenlessthan5yearsofagebutsymptomaticinfectiousmononucleosisoccursinallagegroupsexceptchildhood.

大多数发生5岁以下儿童的初始感染无症状，但有症状的传染性单核细胞增多症在除儿童外的所有年龄组中都发生。

Thedisorderisusuallysuspectedclinicallyandlymphocytosiswith10%to20%atypicallymphocytesisusuallynotedonexaminationoftheperipheralbloodsmear.ThediagnosisisconfirmedserologicallybytheMonospottestorbythemorespecificEBVantibodytiterstudies.Inadditiontotheperipheralbloodfindings,thebonemarrowisofteninvolved,althoughnotfrequentlysampled.

当外周血涂片检查常发现10%至20%不典型淋巴细胞的淋巴细胞增多时临床常怀疑为该病。诊断通过血清学的单点试验或更特异的EBV抗体滴度研究得到证实。除了外周血象外，骨髓也常受累，尽管不常取样。

形态学特点：

Animmunoblasticproliferationisthecharacteristicfeature,ac